Antimicrobial stewardship programs that target only high-cost, broad-spectrum antimicrobials miss opportunities to reduce Clostridium difficile infections
Most patients who developed Clostridium difficile infection received antimicrobials not audited by the antimicrobial stewardship program. Inappropriate antimicrobial use commonly involved nonaudited antimicrobials. Antimicrobial stewardship programs that focus only on high-cost antimicrobials miss opportunities to reduce Clostridium difficile infections.