Currently BMPs are clinically used in spinal fusion, oral and maxillofacial surgery and also in repair of long bone defects.

Different types of carrier materials are used: natural, synthetic polymers, calcium phosphate and ceramic-polymer composite

Efficacy and application of BMPs in various levels with proper carrier and dose is yet to be established

Number of research articles has been published on minute intricacies of loading process and release kinetics of BMPs

Present article collates success, limitation and identifies prospects, challenges for use of BMPs in orthopaedic surgery.