Enzymatically-gellable galactosylated chitosan: Hydrogel characteristics and hepatic cell behavior
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- 作者：Ali Baradar Khoshfetrata ; khoshfetrat@sut.ac.ir" class="auth_mail" title="E-mail the corresponding author ; Mehdi Khanmohammadib ; mehdi-khanmohammadi@cheng.es.osaka-u.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Shinji Sakaib ; sakai@cheng.es.osaka-u.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Masahito Tayab ; taya@cheng.es.osaka-u.ac.jp" class="auth_mail" title="E-mail the corresponding author
- 关键词：Ph ; phenolic hydroxyl ; La ; lactobionic acid ; HRP ; horseradish peroxidase ; NHS ; N-hydroxysulfosuccinimide ; TEMED ; tetramethylethylenediamine ; pHP ; 3-(p-hydroxyphenyl) propionic acid ; WSCD ; water soluble 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide ; PBS ; phosphate-buffered saline ; CF-KRH ; calcium-free krebs rninger hepes-buffered saline ; HepG2 ; hepatoma cell line ; 1HNMR ; Proton nuclear magnetic response ; FBS ; fetal bovine serum ; DMEM ; dulbecco⿿s modified eagles medium ; MES ; morpholinoethanesulfo
- 刊名：International Journal of Biological Macromolecules
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：92
- 期：Complete
- 页码：892-899
- 全文大小：1966 K
文摘
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Both galactose and phenolic hydroxyl moieties were incorporated into chitosan.
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Gelation time decreased with increasing incorporation of phenolic hydroxyl groups.
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Hydrogel mechanical property was improved by increasing galactose moiety content.
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20">Content of galactose groups modulated HepG2 cell behaviors on the resultant gels.