Developing easy to perform routine MRI measurements as potential surrogates for cognitive impairment in MS

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• 作者：Sarah A. Morrow^a ; ^b ; ^{Sarah.morrow@lhsc.on.ca} ; Suresh Menon^a ; ^d ; Heather Rosehart^a ; Manas Sharma^c
• 关键词：Multiple sclerosis ; Cognitive impairment ; MRI ; Atrophy ; Biomarker
• 刊名：Clinical Neurology and Neurosurgery
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：153
• 期：Complete
• 页码：73-78
• 全文大小：1189 K
• 卷排序：153

文摘

Cognitive impairment is common in persons with Multiple Sclerosis. MRI would be a useful biomarker for cognitive impairment as it used frequently in clinical practice. This study examined simple MRI measures and cognition in persons with MS. Larger bicaudate width was associated with impaired immediate recall. Smaller corpus callosum measures were associated with impairment in several domains.