Nedd8 targets ubiquitin ligase Smurf2 for neddylation and promote its degradation
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- 作者：Jingyi Shua ; b ; 1 ; Chao Liua ; b ; 1 ; Rongfei Weib ; Ping Xiec ; Shan Heb ; Lingqiang Zhangb ; zhanglq@nic.bmi.ac.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Protein neddylation ; Protein ubiquitination ; Nedd8 ; Ubiquitin ligase ; Smurf2
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：20 May 2016
- 年：2016
- 卷：474
- 期：1
- 页码：51-56
- 全文大小：954 K
文摘
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Nedd8 promotes degradation of Smurf2.
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Smurf2 is substrate of neddylation.
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Smurf2 neddylation promotes its ubiquitination.
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Smurf2 is a potential neddylation E3.