Molecular mechanism of Antrodia cinnamomea sulfated polysaccharide on the suppression of lung cancer cell growth and migration via induction of transforming growth factor β receptor degradation
刊名:International Journal of Biological Macromolecules
出版年:2017
出版时间:February 2017
年:2017
卷:95
期:Complete
页码:1144-1152
全文大小:3149 K
卷排序:95
文摘
SPS inhibits the viability of lung cancer cells via the induction of cell cycle arrest. SPS activates caspase 3 and PARP. SPS inhibits TGFβ-mediated signaling pathways and cell migration. SPS induces proteasome-dependent TGFβ receptor degradation.