Validated spectrofluorimetric methods for the determination of apixaban and tirofiban hydrochloride in pharmaceutical formulations

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• 作者：Ramzia I. El-Bagary^a ; ^b ; Ehab F. Elkady^b ; Naira A. Farid^c ; ^{nairaahmed49@yahoo.com} ; Nadia F. Youssef^c
• 关键词：Spectrofluorimetry ; Apixaban ; Tirofiban HCl ; Method validation ; Pharmaceutical formulations
• 刊名：Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
• 出版年：2017
• 出版时间：5 March 2017
• 年：2017
• 卷：174
• 期：Complete
• 页码：326-330
• 全文大小：511 K
• 卷排序：174

文摘

New validated spectrofluorimetric methods for the analysis of selected anticoagulants. The developed methods are successfully applied for the analysis of selected drugs in drug substances and drug products. The methods are based on the measurements of the native fluorescence of selected drugs. The proposed methods can be used as alternative methods in quality control laboratories.