Ameliorative effect of riboflavin on hyperglycemia, oxidative stress and DNA damage in type-2 diabetic mice: Mechanistic and therapeutic strategies
详细信息 查看全文
- 作者：Md. Maroof Alam ; Sarah Iqbal ; Imrana Naseem ; imrananaseem2009@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Riboflavin ; Oxidative stress ; Glutathione reductase ; GLUT-4 ; DNA damage
- 刊名：Archives of Biochemistry and Biophysics
- 出版年：2015
- 出版时间：15 October 2015
- 年：2015
- 卷：584
- 期：Complete
- 页码：10-19
- 全文大小：2124 K
文摘
- •
Riboflavin (RF) ameliorates oxidative stress and DNA damage in diabetic mice.
- •
Photo-illuminated RF act as pro-oxidant while non-illuminated act as an antioxidant.
- •
RF showed a significant recovery in liver and kidney marker enzymes and tissue damage.
- •
RF as a dietary compound might help in the reduction of damage caused by metabolic diseases.