Patronin/Shot Cortical Foci Assemble the Noncentrosomal Microtubule Array that Specifies the Drosophila Anterior-Posterior Axis
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- 作者：Dmitry Nashchekin1 ; Artur Ribeiro Fernandes1 ; Daniel St Johnston1 ; d.stjohnston@gurdon.cam.ac.uk" class="auth_mail" title="E-mail the corresponding author
- 刊名：Developmental Cell
- 出版年：2016
- 出版时间：11 July 2016
- 年：2016
- 卷：38
- 期：1
- 页码：61-72
- 全文大小：6424 K
文摘
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The Drosophila spectraplakin, Shot, recruits Patronin to form noncentrosomal MTOCs
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The actin-binding domain of Shot anchors the ncMTOCs to the oocyte cortex
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Par-1 excludes Shot from the posterior cortex to define the anterior-posterior axis
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Shot/Patronin ncMTOCs lack γ-tubulin and grow MTs from stabilized minus-end stumps