Thiazole compounds with activity against Cryptococcus gattii and Cryptococcus neoformans in聽vitro
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- 作者：Ní ; vea Pereira de Sá ;
- 关键词：Cryptococcus ; Antifungal ; Cytotoxicity ; Thiazole
- 刊名：European Journal of Medicinal Chemistry
- 出版年：2015
- 出版时间：18 September 2015
- 年：2015
- 卷：102
- 期：Complete
- 页码：233-242
- 全文大小：603 K
文摘
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We developed some thiazole heterocyclic compounds with promising antifungal activity.
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The thiazole displayed low cytotoxicity and significant antifungal activity.
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The selected thiazoles can be used as prototypes for the design of new antifungal drugs.