Subunit NDUFV3 is present in two distinct isoforms in mammalian complex I

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• 作者：Hannah R. Bridges¹ ; Khairunnisa Mohammed¹ ; Michael E. Harbour ; Judy Hirst ; ^{jh@mrc-mbu.cam.ac.uk}
• 关键词：Complex I ; isoform ; mitochondria ; NADH ; ubiquinone oxidoreductase ; NDUFV3 ; rat
• 刊名：Biochimica et Biophysica Acta (BBA) - Bioenergetics
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：1858
• 期：3
• 页码：197-207
• 全文大小：1976 K
• 卷排序：1858

文摘

Rat complex I contains the same 45 subunits as bovine complex I Complex I subunit NDUFV3 is present in two isoforms, a short and a long isoform The abundance of the long NDUFV3 isoform in complex I is tissue dependent The long NDUFV3 isoform is a ~ 50 kDa protein with unstructured regions