Prediction of microRNAs involved in immune system diseases through network based features

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• 作者：Archana Prabahar ^{archana.prabahar@gmail.com} ; Jeyakumar Natarajan ; ^{n.jeyakumar@yahoo.co.in}
• 关键词：miRNA ; Immune diseases ; Network ; Topological features ; SVM ; Classification
• 刊名：Journal of Biomedical Informatics
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：65
• 期：Complete
• 页码：34-45
• 全文大小：2129 K
• 卷排序：65

文摘

We present an immune miRNA classifier based on novel network and motif features. Our integrated approach aims to discriminate immune miRNAs from non-immune miRNAs. The combined network, motif, sequence and structure features provides better accuracy. The proposed method can be used to discriminate immune miRNAs with better accuracy.