Poor sleep quality is associated with greater circulating pro-inflammatory cytokines and severity and frequency of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) symptoms in women

详细信息    查看全文

• 作者：Sara F. Milrad^a ; Daniel L. Hall^b ; Devika R. Jutagir^a ; Emily G. Lattie^c ; Gail H. Ironson^a ; William Wohlgemuth^d ; Maria Vera Nunez^f ; Lina Garcia^e ; Sara J. Czaja^e ; Dolores M. Perdomo^e ; Mary Ann Fletcher^f ; Nancy Klimas^f ; Michael H. Antoni^a ; ^{mantoni@miami.edu}
• 关键词：Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) ; Poor sleep quality ; Pro-inflammatory cytokines ; Inflammation ; Fatigue
• 刊名：Journal of Neuroimmunology
• 出版年：2017
• 出版时间：15 February 2017
• 年：2017
• 卷：303
• 期：Complete
• 页码：43-50
• 全文大小：533 K
• 卷排序：303

文摘

Sleep quality, inflammation, and CFS/ME symptoms were analyzed. Poor sleep quality predicted pro-inflammatory cytokines IL-1β, IL-6, and TNF-α. Worse sleep quality related to greater fatigue severity and daily interference. Worse sleep quality related to more severe and frequent CFS/ME symptoms. Further research is needed to identify the etiology of sleep disruptions in CFS/ME.