Combined isolated trigeminal and facial neuropathies from perineural invasion by squamous cell carcinoma: A case series and review of the literature

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• 作者：Pierre R. Bourque^a ; ^b ; ^d ; ^{pbourque@toh.ca} ; Gabrielle Bourque^c ; ^{gabrielle.bourque3@usherbrooke.ca} ; William Miller^b ; ^e ; ^{wmiller@toh.ca} ; John Woulfe^b ; ^d ; ^{jwoulfe@toh.ca} ; Jodi Warman Chardon^a ; ^b ; ^d ; ^f ; ^g ; ^{jwarman@toh.ca}
• 关键词：Perineural invasion ; Trigeminal neuropathy ; Facial neuropathy ; Squamous cell carcinoma
• 刊名：Journal of Clinical Neuroscience
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：35
• 期：Complete
• 页码：5-12
• 全文大小：2833 K
• 卷排序：35

文摘

Perineural invasion is a specific form of metastatic spread guided by neurotrophic factors. The trigeminal and facial nerves are the cranial nerves most frequently affected, alone or in combination. The pterygopalatine and auriculotemporal branches are the most relevant trigeminal-facial anastomoses. Neuroimaging of perineural invasion requires attention to specific anatomic locations of interest at the base of the skull.