Cutaneous squamous cell carcinomas with markers of increased metastatic risk are associated with elevated numbers of neutrophils and/or granulocytic myeloid derived suppressor cells
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- 作者：Annika Seddona ; b ; Barry Hockc ; Andrew Millere ; Lukas Freif ; John Pearsond ; Judith McKenziec ; Jeremy Simcockf ; Margaret Curriea ; e ; margaret.currie@otago.ac.nz" class="auth_mail" title="E-mail the corresponding author
- 关键词：Neutrophils ; Cutaneous squamous cell carcinoma ; Tumor features ; Granulocytic myeloid derived suppressor cell
- 刊名：Journal of Dermatological Science
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：83
- 期：2
- 页码：124-130
- 全文大小：1515 K
文摘
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High circulating neutrophil counts are associated with known features of high-risk CSCC and poor overall survival in immunocompetent patients.
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Increased tumor thickness is associated with increased peritumoural and tumor-localised neutrophils.
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The function and prognostic value of neutrophils in CSCC merits further investigation.