Intralesional 5-fluorouracil (FU) as a treatment for nonmelanoma skin cancer (NMSC): A review

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• 作者：Lauren Metterle ; BS ; Christopher Nelson ; MD ; Nishit Patel ; MD ; ^{nishitpatelmd@gmail.com" class="auth_mail" title="E-mail the corresponding author}
• 关键词：basal cell carcinoma ; 5-fluorouracil ; intralesional ; management ; medical therapy ; nonmelanoma skin cancer ; squamous cell carcinoma
• 刊名：Journal of the American Academy of Dermatology
• 出版年：2016
• 出版时间：March 2016
• 年：2016
• 卷：74
• 期：3
• 页码：552-557
• 全文大小：222 K

文摘

The treatment paradigm for nonmelanoma skin cancer remains surgical. This fact combined with its remarkably high incidence positions it as the fifth most costly cancer to treat in the Medicare population. To address this, consideration of alternative medical therapeutics is warranted. Intralesional 5-fluorouracil is a potentially affordable option that may demand further investigation. This literature review examines current data on its efficacy and adverse effects.