Risk Stratification in Arrhythmic Right Ventricular Cardiomyopathy Without Implantable Cardioverter-Defibrillators

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• 作者：Francesca Brun ; MD^a ; Judith A. Groeneweg ; MD^b ; ^c ; Kathleen Gear ; RN^c ; Gianfranco Sinagra ; MD^a ; Jeroen van der Heijden ; MD^b ; Luisa Mestroni ; MD^d ; Richard N. Hauer ; MD^b ; ^e ; Mark Borgstrom ; PhD^f ; Trina Hughes ; CCRP^c ; Frank I. Marcus ; MD^c ; ^{fmarcus@u.arizona.edu" class="auth_mail" title="E-mail the corresponding author}
• 关键词：arrhythmogenic right ventricular cardiomyopathy ; arrhythmogenesis ; risk stratification in ARVC
• 刊名：JACC: Clinical Electrophysiology
• 出版年：2016
• 出版时间：October 2016
• 年：2016
• 卷：2
• 期：5
• 页码：558-564
• 全文大小：314 K

文摘

The primary objective of this study is risk stratification of patients with arrhythmic right ventricular cardiomyopathy (ARVC).

Background

There is a need to identify those who need an automatic implantable cardioverter-defibrillator (ICD) to prevent sudden death.

Methods

This is an analysis of 88 patients with ARVC from 3 centers and who were not treated with an ICD.

Results

Risk factors for subsequent arrhythmic deaths were pre-enrollment sustained or nonsustained ventricular tachycardia and decreased left ventricular function.

Conclusions

These factors serve as proposed guidelines for implantation of an ICD in patients with ARVC to prevent sudden death.