Expression of RBPJ and MAML3 increases under hypoxia but not normoxia conditions.
RBPJ and MAML3 play important roles for hypoxia-induced upregulation of SMO.
RBPJ and MAML3 contribute to the activation of Hedgehog signaling under hypoxia.
RBPJ and MAML3 contribute to proliferation and invasiveness in pancreatic cancer.
RBPJ and MAML3 could be therapeutic targets for pancreatic cancer.