Diaphragmatic fatigue during inspiratory muscle loading in normoxia and hypoxia
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- 作者：David Johannes Walkera ; b ; david.walker@klinikum-konstanz.de" class="auth_mail" title="E-mail the corresponding author ; Franziska Farquharsona ; b ; Hannes Klenzea ; b ; Stephan Walterspachera ; Lucia Storzb ; Daniel Duerschmiedc ; Kai Roeckerd ; Hans-Joachim Kabitza
- 关键词：Diaphragm ; Hypoxic effects ; Twitch transdiaphragmatic pressure ; Inspiratory muscle loading ; Threshold loading
- 刊名：Respiratory Physiology & Neurobiology
- 出版年：2016
- 出版时间：15 June 2016
- 年：2016
- 卷：227
- 期：Complete
- 页码：1-8
- 全文大小：639 K
文摘
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We investigated the effect of hypoxia on the progression of diaphragmatic fatigue during inspiratory muscle loading.
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In normoxia the progression of diaphragmatic fatigue during inspiratory muscle loading follows an exponential decay.
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In hypoxia the progression of diaphragmatic fatigue during inspiratory muscle loading follows a linear decline.