Characterization of a protein tyrosine phosphatase as a host factor promoting baculovirus replication in silkworm, Bombyx mori
详细信息 查看全文
- 作者：Fei Wang ; Renju Xue ; Xianyang Li ; Cuimei Hu ; Qingyou Xia ; xiaqy@swu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Protein tyrosine phosphatase ; Bombyx mori ; BmPTP-h ; Nucleopolyhedrovirus ; Viral replication
- 刊名：Developmental & Comparative Immunology
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：57
- 期：Complete
- 页码：31-37
- 全文大小：1142 K
文摘
- •
36 PTP genes were identified and classified in silkworm genome.
- •
BmNPV infection potently induced the expression of Bmptp-h.
- •
BmPTP-h has catalytic activity.
- •
Knock-down of Bmptp-h by RNAi significantly inhibited baculovirus replication.
- •
Over-expression of Bmptp-h enhanced baculovirus replication.