文摘
Oxyresveratrol (OXY) increased TFF3 expression in LS 174T goblet cells. Conditioned medium was prepared from goblet cells treated with OXY (GCO-CM). GCO-CM increased the expression levels of claudin-1, occludin, and ZO-1. GCO-CM significantly increased tight junction integrity and reduced permeability. OXY strengthened tight junctions by stimulating TFF3 production in goblet cells.