Diamond micro-cantilevers as transducers for olfactory receptors - based biosensors: Application to the receptors M71 and OR7D4
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- 作者：R. Manaia ; M. HabchiaAuthor Vitae ; D. Kamouni-BelghitiaAuthor Vitae ; M.A. Persuyb ; L. RousseaucAuthor Vitae ; M. Possas AbreucAuthor Vitae ; D. Grebertb ; K. Badonnelb ; P. BergonzoaAuthor Vitae ; E. Pajot-AugybAuthor Vitae ; G. SanzbAuthor Vitae ; E. Scorsonea ; emmanuel.scorsone@cea.fr" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae
- 关键词：EIS ; Electrochemical Impedance Spectroscopy ; BDD ; Boron Doped Diamond
- 刊名：Sensors & Actuators: B. Chemical
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：238
- 期：Complete
- 页码：1199-1206
- 全文大小：1547 K
文摘
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Immobilization of two olfactory receptors (M71 and OR7D4) onto diamond transducers is proposed.
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Two different grafting procedures are monitored by EIS on BDD surfaces and micro-cantilevers.
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Odorant detection is suggested in liquid phase using Laser Doppler read-out system.
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M71 shows a good sensitivity to acetophenone and selectivity against 2-octanone.
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OR7D4 sensor shows a good sensitivity to androstenone with selectivity against acetophenone and 2-octanone.