Central auditory function of deafness genes
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- 作者：Marc A. Willaredta ; Lena Ebbersa ; Hans Gerd Nothwanga ; b ; hans.g.nothwang@uni-oldenburg.de" class="auth_mail
- 关键词：ABR ; auditory brainstem response ; AVCN ; anterior ventral cochlear nucleus ; CNC ; cochlear nucleus complex ; DCN ; dorsal cochlear nucleus ; IHC ; inner hair cell ; LSO ; lateral superior olive ; MNTB ; medial nucleus of the trapezoid body ; OHC ; outer hair cell ; PVCN ; posterior ventral cochlear nucleus ; r ; rhombomere ; SOC ; superior olivary complex ; SPN ; spiral ganglion neuron ; TF ; transcription factor
- 刊名：Hearing Research
- 出版年：June 2014
- 年：2014
- 卷：312
- 期：Complete
- 页码：9-20
- 全文大小：903 K
文摘
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Analyses of transgenic mice show substantial central auditory function of deafness genes.
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Deafness genes are enriched in the transcriptome of the auditory brainstem.
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Shared genetic program during development of peripheral and central auditory system.
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Novel sequencing techniques will allow affordable genetic diagnosis.
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Knowledge of central auditory function will aid personalized hearing devices.