miR-1207-3p regulates the androgen receptor in prostate cancer via FNDC1/fibronectin
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- 作者：Dibash K. Dasa ; b ; h ; Michelle Naidooa ; Adeodat Ilboudoa ; Jong Y. Parkc ; Thahmina Alia ; Konstantinos Krampisa ; d ; Brian D. Robinsone ; f ; Joseph R. Osborneg ; Olorunseun O. Ogunwobia ; b ; h ; ogunwobi@genectr.hunter.cuny.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：PCa ; prostate cancer ; miR-1207-3p ; microRNA-1207-3p ; FNDC1 ; fibronectin type III domain containing 1 ; FN1 ; fibronectin ; AR ; androgen receptor ; GWAS ; Genome-wide association studies ; UTR ; untranslated region
- 刊名：Experimental Cell Research
- 出版年：2016
- 出版时间：1 November 2016
- 年：2016
- 卷：348
- 期：2
- 页码：190-200
- 全文大小：2947 K
文摘
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Expression of microRNA-1207-3p is significantly lost in prostate cancer (PCa) cells.
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MicroRNA-1207-3p regulates proliferation, apoptosis, and migration via direct molecular targeting of the 3′UTR of FNDC1.
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MicroRNA-1207-3p regulates proliferation, apoptosis, and migration via direct molecular targeting of the 3′UTR of FNDC1.
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FNDC1, FN1, and AR are concurrently overexpressed in metastatic PCa.