Synthesis and in vitro anti-bacterial evaluation of tetracyclic-ortho-fused 4H-naphtho[1′,2′–5,6]pyrano[3,4-d](1,2,3)selenadiazole and its derivatives

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• 作者：A.V. Karnik ; A.M. Kulkarni ; N.J. Malviya ; B.R. Mourya ; B.L. Jadhav
• 关键词：Anti-bacterial activity ; Semicarbazones ; Annulation ; 1 ; 2 ; 3-Selenadiazole ; Naphthopyran
• 刊名：European Journal of Medicinal Chemistry
• 出版年：2008
• 出版时间：November 2008
• 年：2008
• 卷：43
• 期：11
• 页码：2615-2617
• 全文大小：143 K

文摘

Synthesis of new heterocyclic compounds 3a–e containing naphthopyran and selenadiazole as the heterocyclic sub-units in the molecule is achieved using high yielding synthetic protocol. These molecules 3a–e have shown moderate anti-bacterial activity against some gram-positive and gram-negative bacterias.