A Knockout Screen of ApiAP2 Genes Reveals Networks of Interacting Transcriptional Regulators Controlling the Plasmodium Life Cycle

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• 作者：Katarzyna Modrzynskap>1p>p> ; p>p>2p>p> ; p>p>4p>p> ; p>p>km8@sanger.ac.ukp> ; Claudia Pfanderp>1p> ; Lia Chappellp>1p> ; Lu Yup>1p> ; Catherine Suarezp>1p>p> ; p>p>3p> ; Kirsten Dundasp>1p> ; Ana Rita Gomesp>1p> ; David Gouldingp>1p> ; Julian C. Raynerp>1p> ; Jyoti Choudharyp>1p> ; Oliver Billkerp>1p>p> ; p>p>ob4@sanger.ac.ukp>
• 关键词：ap2-o ; ap2-o2 ; ap2-o3 ; ap2-o4 ; ap2-sp ; ap2-sp2 ; ap2-sp3 ; ap2-l ; Apetala 2 ; oocyst
• 刊名：Cell Host & Microbe
• 出版年：2017
• 出版时间：11 January 2017
• 年：2017
• 卷：21
• 期：1
• 页码：11-22
• 全文大小：3982 K
• 卷排序：21

文摘

Mutants in 11 of 26 apiAP2 genes reveal gene functions in mosquito transmission Co-expression clustering across mutants and stages reveals molecular phenotypes Multifunctional apiAP2 genes create complex regulatory networks in Plasmodium Ap2-g2 is a transcriptional repressor in both asexual and sexual blood stages