A review of adenoid cystic carcinoma of the breast with emphasis on its molecular and genetic characteristics

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• 作者：Semir Vranic ; MD^a ; Richard Bender ; MD^b ; Juan Palazzo ; MD^c ; Zoran Gatalica ; MD ; DSc^b ; ^{zgatalica@carisls.com}
• 关键词：Breast cancer ; Triple-negative breast carcinoma ; Special types ; Adenoid cystic carcinoma
• 刊名：Human Pathology
• 出版年：2013
• 出版时间：March, 2013
• 年：2013
• 卷：44
• 期：3
• 页码：301-309
• 全文大小：1776 K

文摘

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Summary

Breast carcinomas that do not express estrogen receptor ¦Á, progesterone receptor, or human epidermal growth factor receptor 2 are frequently grouped together as ¡°triple negative¡± and considered an aggressive type of breast malignancy; however, this group is not homogeneous. Adenoid cystic carcinoma of the breast is a rare type of breast cancer with such triple-negative features and, generally, a more favorable clinical course. This comprehensive review describes diagnostic, molecular, and clinical features of adenoid cystic carcinoma and compares them with those of triple-negative breast carcinomas of no special type.