Methylation of the circadian Clock gene in the offspring of a free-living passerine bird increases with maternal and individual exposure to PM₁₀

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• 作者：Andrea Romano^a ; Barbara De Giorgio^b ; Marco Parolini^a ; Chiara Favero^b ; Cristina Daniela Possenti^a ; Simona Iodice^b ; Manuela Caprioli^a ; Diego Rubolini^a ; Roberto Ambrosini^c ; Luca Gianfranceschi^a ; ^{luca.gianfranceschi@unimi.it} ; Nicola Saino^a ; Valentina Bollati^b ; ^{valentina.bollati@unimi.it}
• 关键词：Air pollution ; Barn swallow ; DNA methylation ; Epigenetics ; Clock gene
• 刊名：Environmental Pollution
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：220
• 期：part_PA
• 页码：29-37
• 全文大小：1795 K
• 卷排序：220

文摘

DNA methylation according to airborne PM10 was examined in barn swallow nestlings. Methylation was measured on the Clock gene, which is involved in circannual activities. Methylation increased with PM10 level recorded few days before blood sampling. Methylation increased with PM10 level experienced by the mother during egg laying. Anthropogenic pollution may affect populations in the wild via epigenetic effects.