Deletion of luxS further attenuates the virulence of the avian pathogenic Escherichia coli aroA mutant
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- 作者：Xiangan Hana ; Hao Baia ; b ; Jian Tub ; Lijun Yanga ; Da Xua ; Shaohui Wanga ; Kezong Qib ; Guobo Fana ; Yuxi Zhanga ; b ; Jiakun Zuoa ; Mingxing Tiana ; Chan Dinga ; Shengqing Yua ; yus@shvri.ac.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Avian pathogenic Escherichia coli ; aroA mutant ; luxS ; Pathogenicity
- 刊名：Microbial Pathogenesis
- 出版年：2015
- 出版时间：November 2015
- 年：2015
- 卷：88
- 期：Complete
- 页码：39-47
- 全文大小：2362 K
文摘
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The aroA and luxS double deletion APEC mutant (strain DE17螖luxS螖aroA) were constructed from the APEC DE17 strain.
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The double deletion of luxS and aroA attenuated APEC pathogenicity.
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The mutant strain DE17螖luxS螖aroA was more appropriate for development of a future vaccine.