Clinico-pathological correlation in adenylate kinase 5 autoimmune limbic encephalitis
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- 作者：Adeline S.L. Nga ; Joel Kramera ; Alejandro Centurionb ; Josep Dalmauc ; Eric Huangd ; Jennifer A. Cotterd ; Michael D. Geschwinda ; michael.geschwind@ucsf.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Adenylate kinase 5 ; Autoimmunity ; Limbic encephalitis ; Neuronal antibodies ; Rapidly progressive dementia
- 刊名：Journal of Neuroimmunology
- 出版年：2015
- 出版时间：15 October 2015
- 年：2015
- 卷：287
- 期：Complete
- 页码：31-35
- 全文大小：935 K
文摘
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First reported pathology of adenylate kinase 5 (AK5)-autoimmune limbic encephalitis
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Immunohistochemistry confirms a predominantly cytotoxic T-cell process.
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No evidence of cancer found on autopsy
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AK5 autoimmune limbic encephalitis may not be paraneoplastic in nature.
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AK5 autoimmunity may herald a poorly-responsive or refractory course.