Heavy metals produce toxicity, oxidative stress and apoptosis in the marine teleost fish SAF-1 cell line
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- 作者：Patricia Morcillo ; Marí ; a Á ; . Esteban ; Alberto Cuesta ; alcuesta@um.es" class="auth_mail" title="E-mail the corresponding author
- 关键词：Heavy metal ; Oxidative stress ; Apoptosis ; ROS production ; SAF-1 cell line ; Marine fish
- 刊名：Chemosphere
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：144
- 期：Complete
- 页码：225-233
- 全文大小：1513 K
文摘
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MeHg was the most toxic metal to SAF-1 cells, followed by As, Cd, Hg and Pb.
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SAF-1 cells overproduce ROS in response to metal exposure.
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Heavy metals induced apoptosis cell death.
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Arsenic used different toxicological mechanism than Hg, Cd and Pb.