81. Upper body arterio-central venous PCO₂ gap (UBCO₂G) in monitoring sick children with cardiac disease

详细信息    查看全文

• 作者：Omar Mohammad Hijazi ; Mohamed S. Kabbani ; Abdulraouf M.Z. Jijeh ; Hayan F. Taweel ; Anwar E. Abdulla Al Ghamdi ; Ahmed ; Sameh R. Ismail ; Mahmoud Al Barbary ; Loh W. Ling
• 刊名：Journal of the Saudi Heart Association
• 出版年：2015
• 出版时间：October 2015
• 年：2015
• 卷：27
• 期：4
• 页码：330
• 全文大小：41 K

文摘

To determine the validity of using UBCO₂G for monitoring sick children with cardiac disease.

Design

A prospective, observational non interventional cohort study.

Setting

King Abdul Aziz Medical City, Pediatric Cardiac ICU (PCICU), Riyadh.

Patients

Between April 2011 and May 2013, 257 patients admitted to our PCICU were recruited in the study.

Intervention

Arterial and central venous blood samples were collected as needed per patients’ conditions. Patients’ clinical and laboratory data were collected simultaneously.

Results

A total of 421 data sets with arterial, upper (SVC) and lower (FV) body central venous PCO₂ were collected spontaneously from 257 patients age 17.0 ± 25.8 months, weight 7.45 ± 5.53 kg. UBPCO₂G was higher than lower (art-FV) body PCO₂ (LBPCO₂G) gap 7.80 ± 3.28 vs. 5.95 ± 3.65 mmHg (p = 0.001. In 75% of our data sets UBPCO₂G was 猢?.65 and LBPCO₂ gap was 猢?.8 mmHg. Patients with UBPCO₂G 猢?.65 vs. <9.65 mmHg had higher lactic acid (LA) 2.0 ± 1.4 vs. 1.6 ± 1.3 mmol/L (p = 0.014), BUN 6.1 ± 5.2 vs. 4.8 ± 2.1 mmol/L (p = 0.013), creatinine 48 ± 17 vs. 43 ± 13 渭mol/L (p = 0.004), glucose 8.7 ± 4.1 vs. 7.1 ± 3.7 mmol/L (p = 0.001) and PRISM score 9 ± 6 vs. 7 ± 6 (p = 0.038) and lower urine output 5.2 ± 2.8 vs. 6.1 ± 4.3 ml/kg/3 h. However patients with UBPCO₂G 猢? vs. <6 mmHg were different in LA only 1.8 ± 1.5 vs. 1.5 ± 1.0 mmol/L, respectively (p = 0.018).

Conclusion

Upper is higher than lower body PCO₂gap. UBPCO₂G 猢?.65 was associated with higher LA, BUN, creatinine, serum glucose and PRISM and lower urine output. Patients with UBPCO₂G 猢?.65 were sicker. UBPCO₂G can be used as a biomarker in monitoring children with cardiac disease.