The effects of negative pressure treatment on the extracellular matrix gene expression and protein production of fibroblasts
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- 作者：Pei-Yu Chena ; f92548050@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Chih-Chin Hsub ; c ; steele1@ms10.hinet.net" class="auth_mail" title="E-mail the corresponding author ; Kai-Chiang Yangd ; pumpkin@tmu.edu.tw" class="auth_mail" title="E-mail the corresponding author ; Chang-Chin Wua ; e ; dtorth65@yahoo.com.tw" class="auth_mail" title="E-mail the corresponding author ; Chung-Li Wanga ; f ; chungli@ntu.edu.tw" class="auth_mail" title="E-mail the corresponding author
- 关键词：Wound healing ; Negative pressure wound therapy ; Fibroblast ; Extracellular matrix
- 刊名：Process Biochemistry
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：50
- 期：10
- 页码：1662-1668
- 全文大小：1858 K
文摘
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Negative pressure wound therapy has been suggested for wounds management.
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Periodical NP upregulate Collagen I, III, and fibronectin mRNA in mouse fibroblasts.
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TGF-尾1 protein production was enhanced, but not TIMP-1, pro-MMP-9, decorin, or IL-6.
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Negative pressure regulates extracellular matrix production in mouse fibroblasts.