A fractional motion diffusion model for grading pediatric brain tumors

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• 作者：M. Muge Karaman ; PhD^a ; He Wang ; PhD^e ; Yi Sui ; PhD^a ; ^d ; Herbert H. Engelhard ; MD ; PhD^c ; Yuhua Li ; MD^f ; ¹ ; ^{liyuhua10@sina.com} ; Xiaohong Joe Zhou ; PhD^a ; ^b ; ^c ; ^d ; ¹ ; ^{xjzhou@uic.edu}
• 关键词：Pediatric brain tumor ; Non-Gaussian diffusion models ; Anomalous diffusion ; Fractional motion ; Continuous-time random-walk ; Tumor grading
• 刊名：NeuroImage: Clinical
• 出版年：2016
• 出版时间：2016
• 年：2016
• 卷：12
• 期：Complete
• 页码：707-714
• 全文大小：1250 K
• 卷排序：12

文摘

The fractional motion (FM) diffusion model was applied to pediatric brain tumors. The FM model parameters can be sensitive to tissue microstructures. The FM model outperforms the mono-exponential diffusion model. The FM model performs similarly to the continuous-time random-walk (CTRW) model. Our results challenge those from recent biophysics studies in cell cultures.