056 Mutli-dimensional prevention program after acute coronary syndrome (ELIPS)

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• 作者：Pierre-Fré ; dé ; ric Keller¹ ; Nicolas Rodondi² ; Reto Auer² ; Thomas Perneger³ ; Franck Schneider⁴ ; Ariel Richard-Arlaud⁴ ; Marco Roffi¹ ; David Carballo¹ ; Sebastian Carballo⁵ ; Christian Matter⁶ ; Thomas Luscher⁶ ; Stephan Windecker⁷ ; Pierre Vogt⁸ ; Jacques Cornuz² ; Gé ; rard Waeber⁹ ; Pierre Chopard¹⁰ ; Jean-Claude Chevrolet¹¹ ; Franç ; ois Mach¹
• 刊名：Archives of Cardiovascular Diseases Supplements
• 出版年：2010
• 出版时间：January 2010
• 年：2010
• 卷：2
• 期：1
• 页码：19
• 全文大小：75 K

文摘

Background

Guidelines recommend pharmacologic and lifestyle interventions to reduce recurrence of events in patients with coronary and other atherosclerotic vascular disease. Based on our systematic review of tested interventions, we developed the ELIPS program, a multidimensional secondary prevention program targeting multiple cardiovascular risk factors for patients after an acute coronary syndrome (ACS). This programme targets an increase in prescription rates by physicians and/or long term medication adherence by patients.

Objectives

To demonstrate the effectiveness of the ELIPS programme (Multi-dimEnsionaL preventIon Program after Acute coronary Syndrome), which aims at improving quality of care of patients admitted to hospital with ACS in the Swiss setting.

Methods

A total of 2400 patients will be prospectively included in a multicenter study before and after the implementation of the ELIPS program with a follow-up of 12 months. The primary outcome is a composite of death from any cause, myocardial infarction, documented unstable angina requiring rehospitalization, revascularization (performed at least 30 days after randomization), and stroke. The secondary endpoints are the isolated endpoints of the primary endpoint as well as cardiovascular mortality, and surrogate outcomes such as cardiovascular risk factor control at follow-up.

Expected results

To demonstrate the benefits of the ELIPS program on recurrence rate of cardiovascular events. These results will certainly lead to a generalization of such programs in the field of atherosclerosis.