Effects of serum albumin on the degradation and cytotoxicity of single-walled carbon nanotubes

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• 作者：Yun Ding^a ; Rong Tian^a ; Zhen Yang^b ; Jianfa Chen^b ; Naihao Lu^a ; ^{naihaolu@jxnu.edu.cn}
• 关键词：Single-walled carbon nanotubes ; BSA ; Biodegradation ; Myeloperoxidase ; Peroxynitrite ; Macrophages
• 刊名：Biophysical Chemistry
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：222
• 期：Complete
• 页码：1-6
• 全文大小：968 K
• 卷排序：222

文摘

Binding of BSA could impair MPO-induced SWCNTs degradation in vitro. The degradation degree was more significant for BSA-SWCNTs in activated macrophages. Binding of BSA to SWCNTs reduced cytotoxicity. Biodegraded nanotubes induced less cytotoxicity than the non-degraded nanotubes.