MicroRNA transcriptome profiling of mice brains infected with Japanese encephalitis virus by RNA sequencing
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- 作者：Xin-Feng Lia ; Rui-Bing Caoa ; Jun Luob ; Jian-Ming Fanc ; Jing-Man Wanga ; Yuan-Peng Zhanga ; Jin-Yan Gua ; Xiu-Li Fenga ; Bin Zhoua ; Pu-Yan Chena ; puyanchennj@yeah.net" class="auth_mail" title="E-mail the corresponding author
- 关键词：KEGG ; Kyoto Encyclopedia of Genes and Genomes ; SHIP1 ; Src homology 2-containing inositol phosphatase 1 ; Jak-STAT ; Janus kinase-Signal Transducer and Activator of Transcription ; NF-κB ; nuclear factor of kappa light polypeptide gene enhancer in B-cells ; Ifng ; Interferon gamma ; Il6 ; Interleukin 6 ; Stat1 ; Signal transducer and activator of transcription 1 ; Nos2 ; Nitric oxide synthase 2 ; Epha2 ; Ephrin receptor tyrosine kinase A2 ; Dll1 ; Notch ligand Delta-like 1 ; Mstn ; Myostatin ; Fgf7 ; Fibroblast grow
- 刊名：Infection, Genetics and Evolution
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：39
- 期：Complete
- 页码：249-257
- 全文大小：3818 K
文摘
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We established a JE model in suckling C57BL/6 mice.
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We identified 8 down-regulated and 18 up-regulated microRNAs in response to JEV infection.
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We analyzed the GO terms and KEGG pathways of target genes of modulated microRNAs.
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We constructed networks of microRNAs and their predicted or validated target genes.