Kinetic and functional properties of human mitochondrial phosphoenolpyruvate carboxykinase
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- 作者：Miriam Escó ; sb ; Pedro Latorrea ; b ; Jorge Hidalgoa ; b ; Ramó ; n Hurtado-Guerrerob ; e ; José ; Alberto Carrodeguasb ; c ; d ; carrode@unizar.es" class="auth_mail" title="E-mail the corresponding author ; Pascual Ló ; pez-Buesaa ; b ; plopezbu@unizar.es" class="auth_mail" title="E-mail the corresponding author
- 关键词：Human mitochondrial phosphoenolpyruvate carboxykinase (PCK) ; Purification ; Kinetics ; Gluconeogenesis ; Glyceroneogenesis
- 刊名：Biochemistry and Biophysics Reports
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：7
- 期：Complete
- 页码：124-129
- 全文大小：634 K
文摘
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Purification of recombinant human PCK2 has been performed.
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10">Its kinetic behavior is very similar to that of human PCK1.
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15">PCK2 overexpression increases gluconeogenesis and glyceroneogenesis in cell cultures.