Melanopsin: The Tale of the Tail

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• 作者：Russell N. Van Gelder¹ ; ² ; ³ ; ^{russvg@uw.edu" class="auth_mail" title="E-mail the corresponding author} ; Ethan D. Buhr¹
• 关键词：Melanopsin ; retina ; intrinsically photosensitive retinal ganglion cell ; phosphorylation
• 刊名：Neuron
• 出版年：2016
• 出版时间：1 June 2016
• 年：2016
• 卷：90
• 期：5
• 页码：909-911
• 全文大小：458 K

文摘

In this issue of Neuron, Mure et al. (2016) demonstrate that two mechanisms—phosphorylation of a C-terminal intracellular region, and mechanism involving the whole of the C terminus—oppositely shape the kinetics and sensitivity of the nonvisual photoreceptor melanopsin.