Hybrid systems based on gold nanostructures and porphyrins as promising photosensitizers for photodynamic therapy

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• 作者：Daniele C. Ferreira^a ; ^{daniele.c.fer@gmail.com} ; Camila S. Monteiro^b ; Claudilene R. Chaves^a ; Gustavo A.M. Sá ; far^a ; Roberto L. Moreira^a ; Maurí ; cio V.B. Pinheiro^a ; Dayse C.S. Martins^b ; Luiz Orlando Ladeira^a ; Klaus Krambrock^a
• 关键词：Photodynamic therapy (PDT) ; Porphyrin ; Gold nanorods ; Gold nanoparticles ; Reactive oxygen species (ROS)
• 刊名：Colloids and Surfaces B: Biointerfaces
• 出版年：2017
• 出版时间：1 February 2017
• 年：2017
• 卷：150
• 期：Complete
• 页码：297-307
• 全文大小：1580 K
• 卷排序：150

文摘

AuNR/POR hybrids show much higher efficiency in 1O2 production than porphyrin. Enhancement effect is stronger for anisotropic AuNR compared with spherical AuNP. Surface charge of AuNR or AuNP has minor effect on 1O2 production of the hybrid. Dominant mechanism for AuNR/POR hybrid in ROS generation for PDT is of type II.