Prostate biopsies, most often performed transrectally, are essential for the diagnosis and assessment of prognosis of prostate cancer. Biopsy localization accuracy is questionable. The development of computer systems allow to record their precise location and guide them to improve their distribution. These same devices can merge ultrasound images and MRI images and merge different sets of biopsies. All these data could be transferred inside ultrasound HIFU systems in order to make focal treatment protocols more accurate.