Effects of PCB 126 and PCB 153 on secretion of steroid hormones and mRNA expression of steroidogenic genes (STAR, HSD3B, CYP19A1) and estrogen receptors (ERα, ERβ) in prehierarchical chicken ovarian follicles
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- 作者：Andrzej Sechman ; rzsechma@cyf-kr.edu.pl ; Marta Batoryna ; Piotr A. Antos ; Anna Hrabia
- 关键词：PCB 126 ; PCB 153 ; Steroidogenesis ; Estrogen receptors ; Chicken ovary
- 刊名：Toxicology Letters
- 出版年：2016
- 出版时间：15 December 2016
- 年：2016
- 卷：264
- 期：Complete
- 页码：29-37
- 全文大小：1060 K
- 卷排序：264
文摘
PCB 126 and PCB 153 affect steroid secretion by prehierarchical (PF) chicken ovarian follicles. Both PCBs influence STAR, HSD3B, CYP19A1, ERα and ERβ mRNA expression. PCBs may impair development and selection of PF follicles to preovulatory hierarchy.