Out of Africa: origins and evolution of the human malaria parasites Plasmodium falciparum and Plasmodium vivax

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• 作者：Dorothy E. Loy^a ; ^b ; Weimin Liu^a ; Yingying Li^a ; Gerald H. Learn^a ; Lindsey J. Plenderleith^c ; Sesh A. Sundararaman^a ; ^b ; Paul M. Sharp^c ; Beatrice H. Hahn^a ; ^b ; ^{bhahn@upenn.edu}
• 关键词：Malaria ; African apes ; Plasmodium falciparum ; Plasmodium vivax ; Laverania ; Zoonotic transmission ; Evolution
• 刊名：International Journal for Parasitology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：47
• 期：2-3
• 页码：87-97
• 全文大小：1625 K
• 卷排序：47

文摘

Chimpanzees and gorillas harbour six Laverania spp. as well as Plasmodium vivax. Plasmodium falciparum arose in humans after the acquisition of the parasite from a gorilla. Plasmodium vivax is a bottlenecked parasite lineage that originated in African apes.