Polyostotic Lymphoma in a Ferret (Mustela putorius furo)

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• 作者：H. Long^&lowast ; ; N. di Girolamo^&dagger ; ; P. Selleri^&dagger ; ; C. Palmieri^&lowast ; ; ^{c.palmieri@uq.edu.au" class="auth_mail" title="E-mail the corresponding author}
• 关键词：ferret ; immunohistochemistry ; lymphoma ; polyostotic
• 刊名：Journal of Comparative Pathology
• 出版年：2016
• 出版时间：May 2016
• 年：2016
• 卷：154
• 期：4
• 页码：341-344
• 全文大小：1197 K

文摘

An 8.5-year-old, neutered female ferret (Mustela putorius furo) was presented with tachypnoea, polyuria, polydipsia, anorexia and depression. Radiographs revealed multiple osteolytic lesions of the bone, characterized cytologically by the infiltration of medium- to large-sized lymphocytes. The animal was humanely destroyed and post-mortem examination revealed multifocal masses obliterating the bone marrow of the mandible, right and left humeri and femur, and consisting of an infiltrative population of neoplastic lymphocytes. Immunohistochemical labelling for CD3 and CD79a revealed a CD3-positive neoplastic population. A diagnosis of polyostotic T-cell lymphoma was made, which is the first report of this condition in a ferret.