Lupus nephritis: When and how often to biopsy and what does it mean?
详细信息 查看全文
- 作者：Gabriella Moronia ; gmoroni@policlinico.mi.it" class="auth_mail" title="E-mail the corresponding author ; Federica Depetria ; federica.depetri@unimi.it" class="auth_mail" title="E-mail the corresponding author ; Claudio Ponticellib ; ponticelli.claudio@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Lupus nephritis ; Renal biopsy in SLE ; Repeat renal biopsy ; Lupus class transformation
- 刊名：Journal of Autoimmunity
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：74
- 期：Complete
- 页码：27-40
- 全文大小：1883 K
文摘
- •
Baseline renal biopsy is of paramount value in assessing diagnosis and treatment of lupus nephritis.
- •
The histological class and severity of lupus nephritis cannot be predicted by the clinical features.
- •
Renal biopsy in lupus patients may diagnose other glomerular diseases not directly related to SLE.
- •
Repeat biopsy can recognize histological class transformations and predict long-term outcome.
- •
Repeat renal biopsy are of help in modulating therapy in refractory and relapsing lupus nephritis.