ERP C250 shows the elderly (cognitively normal, Alzheimer’s disease) store more stimuli in short-term memory than Young Adults do
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- 作者：Robert M. Chapmana ; rmc@cvs.rochester.edu" class="auth_mail" title="E-mail the corresponding author ; Margaret N. Gardnera ; Mark Mapstoneb ; Rafael Klormanc ; Anton P. Porsteinssond ; Haley M. Dupreea ; Inga M. Antonsdottira ; Lily Kamalyana
- 关键词：Event-Related Potentials (ERP) ; Electrophysiology ; Alzheimer&rsquo ; s disease (AD) ; Short-term memory ; Principal Components Analysis (PCA) ; Short-latency ERP component C250
- 刊名：Clinical Neurophysiology
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：127
- 期：6
- 页码：2423-2435
- 全文大小：1719 K
文摘
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In Young Adults, ERP C250 is more positive when stimuli that need to be later recalled are stored in short-term memory.
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Normal Elderly show similar C250 activation, as well as to other stimuli.
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Alzheimer’s disease subjects are similar to Normal Elderly, except for a “slow start” trial-wise.