Functional magnetic resonance imaging and diffusion tensor imaging in a case of central poststroke pain

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• 作者：Mohamed L. Seghier ; Franç ; ois Lazeyras ; Patrik Vuilleumier ; Armin Schnider ; Antonio Carota
• 关键词：Central pain ; allodynia ; diffusion MRI ; functional MRI ; thalamocortical fibers
• 刊名：The Journal of Pain
• 出版年：2005
• 出版时间：March 2005
• 年：2005
• 卷：6
• 期：3
• 页码：208-212
• 全文大小：232 K

文摘

The role of the lesion location within functional pain systems is not fully understood for central poststroke pain (CPSP) pathogenesis. In a patient with CPSP we used data from both functional magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) for anatomo-functional correlations. Structural MRI showed a small residual cavity confined to the right thalamic ventral posterolateral nucleus and the adjacent posterior arm of the internal capsule. DTI maps showed selective reduction of right sensory thalamocortical fibers. Functional MRI, performed with different thermonociceptive stimuli, showed pain-specific signal changes in the anterior cingulate gyrus (BA 24/32) and in the associative parietal regions (BA 5/7). These findings underline, for CPSP pathogenesis, the role of damage of lateral nociceptive thalamoparietal fibers together with the release of activity of anterior cingulate and posterior parietal regions.

Perspective

In a patient with CPSP, we combined noninvasive neuroimaging techniques (functional and diffusion MRI) to assess the anatomo-functional relationship in CPSP. Our investigations show, for CPSP pathogenesis, the role of damage of lateral nociceptive thalamoparietal fibers together with the release of activity of anterior cingulate and posterior parietal regions.