Activation of D2 autoreceptors alters cocaine-induced locomotion and slows down local field oscillations in the rat ventral tegmental area
详细信息 查看全文
- 作者：Stanislav Koulchitskya ; Charlotte Delairessea ; Thom Beekena ; Alexandre Montefortea ; Julie Dethierb ; Etienne Quertemontc ; Rolf Findeisend ; Eric Bullingerd ; 1 ; Vincent Seutina ; 1 ; V.Seutin@ulg.ac.be" class="auth_mail" title="E-mail the corresponding author
- 关键词：Stereotypies ; Local field potential ; Ventral tegmental area ; Cocaine ; Quinpirole
- 刊名：Neuropharmacology
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：108
- 期：Complete
- 页码：120-127
- 全文大小：1055 K
文摘
- •
This study combines analysis of behavior and local field potentials in the rat ventral tegmental area after administration of dopaminergic drugs.
- •
Co-administration of an autoreceptor-selective dose of quinpirole and cocaine leads to a very specific behavioral pattern consisting of locomotor stereotypies.
- •
These stereotypies are accompanied by a change in the dominant frequency of the local field potentials.