Osteolysis Propensity Among Bilateral Total Hip Arthroplasty Patients

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• 作者：Charles A. Engh MD ; ^† ; ; Henry Ho MS ; Cara C. Powers MD ; Cathy Huynh BS ; Sarah E. Beykirch BS ; Robert H. Hopper Jr PhD ;
• 关键词：primary total hip arthroplasty outcome among bilateral patients ; pelvic and femoral osteolysis ; volumetric polyethylene wear ; computed tomography ; radiographic patient propensity
• 刊名：The Journal of Arthroplasty
• 出版年：2011
• 出版时间：June 2011
• 年：2011
• 卷：26
• 期：4
• 页码：555-561
• 全文大小：433 K

文摘

Because some patients with high wear rates demonstrate extensive osteolysis whereas other patients with similarly high wear rates show little or no evidence of osteolysis, we hypothesized that both polyethylene wear and a patient-specific propensity mediate the development of osteolysis. We evaluated wear and osteolysis using computed tomography and radiographs among 46 patients who had undergone bilateral total hip arthroplasties (THAs). A radiographic patient-specific propensity for osteolysis associated with each THA was quantified by dividing the amount of osteolysis by the volumetric wear. Using a multivariate regression analysis to simultaneously consider the influence of polyethylene wear and patient propensity, we found that both factors are associated with the amount of osteolysis around a THA and that they appear to be of similar importance.