Determination of organophosphate diesters in urine samples by a high-sensitivity method based on ultra high pressure liquid chromatography-triple quadrupole-mass spectrometry
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- 作者：Guanyong Sua ; guanyong.su85@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Robert J. Letchera ; robert.letcher@canada.ca" class="auth_mail" title="E-mail the corresponding author ; Hongxia Yub
- 关键词：Organophosphate flame retardants ; Organophosphate diesters ; UHPLC&ndash ; ESI&ndash ; QqQ&ndash ; MS ; Urine ; Canadian residents
- 刊名：Journal of Chromatography A
- 出版年：2015
- 出版时间：24 December 2015
- 年：2015
- 卷：1426
- 期：Complete
- 页码：154-160
- 全文大小：714 K
文摘
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A method for determination of 7 organophosphate (OP) diesters in urine was developed.
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High ionic strength buffer was chosen as eluent of OP diesters.
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Three UPLC–ESI–QqQ–MS methods were developed/compared.
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UPLC–ESI(+)–QqQ–MS is ideal for chlorinated diesters after methylation.
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Six OP diesters were detected in human urine samples of Canadian residences.